Genomics
Download ReportGene editing, CRISPR, synthetic biology, personalized medicine, longevity research
4Sources
5Concepts
4Entities
| Title | Type | Author | Date | Key Contribution |
|---|---|---|---|---|
| Prime Editing-Installed Suppressor tRNAs for Disease-Agnostic Genome Editing | Paper | David Liu et al. | Nov 2025 | Disease-agnostic prime editing using suppressor tRNAs addresses ~30% of rare genetic diseases caused by nonsense mutations |
| CRISPR Gene Activation Without Cutting DNA | Paper | Merlin Crossley, Kate Quinlan et al. | Jan 2026 | Epigenetic editing reactivates silenced genes by removing methyl groups without DNA cuts — safer Sickle Cell treatment path |
| First-in-Human CRISPR Trial Safely Lowers Cholesterol and Triglycerides | Paper | Luke Laffin, Steven Nissen et al. | Nov 2025 | Single CRISPR infusion targeting ANGPTL3 reduced LDL ~50% and triglycerides ~55% within 2 weeks, sustained 60+ days |
| CRISPR-GPT: AI-Powered Gene Editing Copilot | Paper | Le Cong, Yuanhao Qu, Kaixuan Huang, Russ Altman et al. | Sep 2025 | LLM copilot for gene editing trained on 11 years of expert data — enabled first-attempt success by novice researchers |